乔元彪
1970年2月生,副教授,工学博士。
主要研究方向
现任药物化学学科带头人,药物化学研究团队负责人。现任美国传染病协会会员,担任Biosensors & Bioelectronics,Journal of Colloid & Interface Science,Sensors & Actuators B: Chem,AIDS Research and Human Retroviruses和Journal of HIV and Retrovirus 学术期刊的第一/主要审稿人。
主要学习工作经历
1988-1992,太原理工大学,应用化学系,应用化学本科/学士
2002-2004,武汉大学,化学院,分析化学研究生/硕士
2005-2007,青岛科技大学,化学与分子工程学院,应用化学研究生/博士
研究工作经历
2003-2004,中科院武汉病毒研究所,学术访问。
2008-2010,浙江大学,材料与化学工程学院,化学工程与技术学科博士后。
2011-2017,必赢线路检测中心药化所,学术带头人,2014年,山西医科大学天然药物发现与开发研究团队,学术访问。
主要教学科研成果
1. Development of a phosphorylated Momordica charantia protein system for inhibiting susceptible dose-dependent C. albicans to available antimycotics: an allosteric regulation of protein. European Journal of Pharmaceutical Science 109 (2017) 262–268
2. Dataset on preparation of the phosphorylated counterparts of a Momordica charantia protein for studying antifungal activities against susceptible dose-dependent C. albicans to antimycotics. Data in Brief 15 (2017) 370–375
3. Sulfates of sorghum vinegar residue waste as potential catalysts. Green Processing & Synthesis, GREENPS.2017.0042
4. A review on architecture of the gag-pol ribosomal frameshifting RNA in human immunodeficiency virus: a variability survey of virus genotypes. Journal of Biomolecular Structure and Dynamics 35 (2017) 1629–1653.
5. Zirconium phosphatidylcholine-based nanocapsules as an in vivo degradable drug delivery system of MAP30, a momordica anti-HIV protein. International Journal of Pharmaceutics 483 (2015) 188–199.
6. Crystal structure of bis(1-benzyl-1H-1,2,4-triazole) perchloric acid monosolvate. Acta Crystallographica Section E 70 (2014)
7. 5-(4-hydroxyphenyl)imidazolidine-2,4-dione. Acta Crystallographi ca Section E 70 (2014)
8. Development and validation of a rapid capillary zone electrophoresis method for determining charge variants of mAb. Journal of Chromatography B 906 (2012) 63–68.
9. A novel chemiluminescent ELISA for detecting furaltadone metabolite, 3-amino-5-morpholinomethyl-2-oxazolidone (AMOZ) in fish, egg, honey and shrimp samples Journal of Immunological Methods 395 (2013) 29–36.
10. Twenty-six circulating antigens and two novel diagnostic candidate molecules identified in the serum of canines with experimental acute toxoplasmosis Parasites & Vectors 9 (2016) 374–385.
11.A new μ-oxo dimer iron(III) complex: Synthesis, characterization, and electrocatalysis. Synthesis and Reactivity in Inorganic, Metal-Organic and Nano-Metal Chemistry 42 (2012)711-715.
12. Immobilization of lipase on zirconium nucleotide and its catalytic performance. Chinese Journal of Catalysis 32 (2011) 630-636.
13. Hydrogen peroxide electrochemical detection for the development of protein film-modified sensor. Sensors and Actuators, B 141 (2009) 205-209.
14. Bioconjugation of zirconium uridine monophosphate: Application to myoglobin direct electrochemistry. Biosensors and Bioelectronics 23 (2008) 1244-1249.
15. Composite films of lecithin and heme proteins with electrochemical and electrocatalytic activities. Journal of Colloid and Interface Science 315 (2007) 537-543.
16. Direct electrochemistry of hemoglobin in TATP film: Application in biological sensor. Sensors and Actuators, B: Chemical 124 (2007) 413-420.
17. Hydrogen peroxide biosensor based on the electrochemistry of the myoglobin-TATP composite film. Analytical Letters 40 (2007) 1-9.
18.2-(2,4-Dichlorophenyl)-1H-benzimidazole. Acta Crystallographica Section E 63 (2007).
19.2-(4-Chlorophenyl)-1H-benzimidazole. Acta Crystallographica Section E 62 (2006).
20. A novel catenarian cyano(triphenyl phosphite) copper(I) complex: Synthesis, crystal structure, thermal, voltammetric and spectral properties. Chinese Journal of Chemistry 24 (2006) 1144-1147.
21. 1-(2-Chlorobenzyl)-2-(2-chlorophenyl)-1H-benzimidazole. Acta Crystallographica Section E 62 (2006).
22. O-lsobutyl N-phenylthiocarbamate. Acta Crystallographica Section E 62 (2006).
23. A dinuclear chloro(triphenylphosphito)copper(I) complex, di-μ2-chloro-bis[bis(triphenylphosphito)-copper(I)]. Acta Crystallographica Section E 61 (2005).
Patients:
1.一种人工核酸水解酶及其制备方法201010601155.2.
2.生物基锆盐纳米颗粒材料的制备方法201110005027.6.
3.一种人工蛋白脂质体的制备方法201210023252.7.
4.磺酸钡催化剂及其在合成D,L-对羟基苯海因中的应用201410434176.8.
5.一种醋糟磺化技术及其产品催化乙内酰脲制备的方法2016100771874.
6.一种含有黑豆皮的保健茶及其制备方法201510386848.7.
7.一种高效海因酶表达菌固载化的方法,201410725375.4.
8.3,5-二氯-2-戊酮的合成方法201310718919.X.
Awards:
1. 核苷酸/磷脂锆纳米介质在蛋白工程中的应用研究. 2016.11 山西省科学技术奖(自然类)2015-Z-3-003号.